Chin. J. Org. Chem. ›› 2003, Vol. 23 ›› Issue (8): 880-882. Previous Articles     Next Articles

蛋氨酸合酶催化反应研究VI.3-N-取代-6-甲基尿嘧啶的合成

韩鹏;王孝伟;张志丽;马小艳;刘俊义   

  1. 北京大学药学院化学生物学系
  • 发布日期:2003-08-25

Study on Catalysis of Methionine Synthase VI. Synthesis of 3-N- Substituted-6-methyl Uracil

Han Peng;Wang Xiaowei;Zhang Zhili;Ma Xiaoyan;Liu Junyi   

  1. Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University
  • Published:2003-08-25

3-.N-Substituted-6-methyl uracils were synthesized for the first time using the benzyloxycarbonyloxymethyl moiety as a protective group of 1-nitrogen of uracil ring. Protection, alkylation and deprotection were completed in facil conditions and high yields.

Key words: URACIL, SELECTIVITY, SYNTHESIS

CLC Number: