Study on the Reaction of Arylmethylidenemalononitriles with 4-Hydroxy-1,2-dihydroquinolin-2-one

Chinese Journal of Organic Chemistry ›› 2004, Vol. 24 ›› Issue (12): 1595-1597. Previous Articles Next Articles

芳亚甲基丙二腈和4-羟基喹啉-2-酮反应的研究

王香善^*,a,b,c, 曾兆森^a, 史达清^a,c, 屠树江^a,c, 魏贤勇^b, 宗志敏^b

^a徐州师范大学化学系徐州 221116
^b中国矿业大学化学工程学院徐州 221008
^c江苏省药用植物生物技术重点实验室徐州 221116

收稿日期:2004-02-23 修回日期:2004-04-19 接受日期:2004-06-21 发布日期:2022-09-20
基金资助:
广东省自然科学基金(No. 011097)资助项目

Study on the Reaction of Arylmethylidenemalononitriles with 4-Hydroxy-1,2-dihydroquinolin-2-one

WANG Xiang-Shan^*,a,b,c, ZENG Zhao-Sen^a, SHI Da-Qing^a,c TU Shu-Jiang^a,c, WEI Xian-Yong^b, ZONG Zhi-Min^b

^aDepartment of Chemistry, Xuzhou Normal University, Xuzhou 221116
^bSchool of Chemical Engineering, China University of Mining and Technology, Xuzhou 221008
^cThe Key Laboratory of Biotechnology on Medical Plant of Jiangsu, Xuzhou 221116

Received:2004-02-23 Revised:2004-04-19 Accepted:2004-06-21 Published:2022-09-20
Contact: *E-mail: ceszzp@zsu.edu.cn

Abstract

A series of new 2-amino-3-cyano-4-aryl-5,6-dihydro-4H-pyrano[3,2-c]quinolin-5-one derivatives were synthesized by the reaction of arylmethylidenemalononitriles with 4-hydroxy-1,2-dihydroquinolin-2-one in ethyl alcohol at 80 ℃ catalyzed by piperidine in good yields. The structure of the product was confirmed by X-ray analysis.

Key words: arylmethylidenemalononitrile, 4-hydroxy-1,2-dihydriquinolin-2-one, pyrano[3,2-c]quinolin-5-one, piperidine, synthesis

Cite this article

WANG Xiang-Shan, ZENG Zhao-Sen, SHI Da-Qing TU Shu-Jiang, WEI Xian-Yong, ZONG Zhi-Min. Study on the Reaction of Arylmethylidenemalononitriles with 4-Hydroxy-1,2-dihydroquinolin-2-one[J]. Chinese Journal of Organic Chemistry, 2004, 24(12): 1595-1597.

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芳亚甲基丙二腈和4-羟基喹啉-2-酮反应的研究

Study on the Reaction of Arylmethylidenemalononitriles with 4-Hydroxy-1,2-dihydroquinolin-2-one

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