Synthesis of 9-Arylpolyhydroacridine in Water Catalyzed by Triethylbenzylammonium Chloride (TEBA)

Chinese Journal of Organic Chemistry ›› 2004, Vol. 24 ›› Issue (4): 430-432. Previous Articles Next Articles

三乙基苄基氯化铵(TEBA)催化下水中9-芳基多氢吖啶衍生物的合成

王香善^*, 史达清, 张燕飞, 王苏惠, 屠树江

徐州师范大学化学系江苏省药用植物生物技术重点实验室徐州 221116

收稿日期:2003-06-17 修回日期:2003-08-21 接受日期:2003-10-14 发布日期:2022-09-19
基金资助:
江苏省青蓝工程基金(No. QL98001)和徐州师范大学校重点基金(No. 02AXL004)资助项目

Synthesis of 9-Arylpolyhydroacridine in Water Catalyzed by Triethylbenzylammonium Chloride (TEBA)

WANG, Xiang-Shan^*, SHI, Da-Qing, ZHANG, Yan-Fei, WANG, Su-Hui, TU, Shu-Jiang

Department of Chemistry, Xuzhou Normal University, Key Laboratory of Biotechnology on Medical Plant, Xuzhou 221116

Received:2003-06-17 Revised:2003-08-21 Accepted:2003-10-14 Published:2022-09-19
Contact: *E-mail: xswang@xznu.edu.cn

Abstract

A series of 3,3,6,6-tetramethyl-1,8-dioxo-9-aryl-1,2,3,4,5,6,7,8,9,10-decahydro-acridines have been synthesized by the condensation of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione and ammonium acetate in the presenceof triethylbenzylammonium chloride (TEBA) as catalyst in water. Compared with other solvents, water is cheap, not inflammable and not toxic, and the yields of the reaction are high. The structure of 3e was confirmed by X-ray analyses.

Key words: decahydro-acridines, water, TEBA, synthesis

Cite this article

WANG, Xiang-Shan, SHI, Da-Qing, ZHANG, Yan-Fei, WANG, Su-Hui, TU, Shu-Jiang. Synthesis of 9-Arylpolyhydroacridine in Water Catalyzed by Triethylbenzylammonium Chloride (TEBA)[J]. Chinese Journal of Organic Chemistry, 2004, 24(4): 430-432.

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三乙基苄基氯化铵(TEBA)催化下水中9-芳基多氢吖啶衍生物的合成

Synthesis of 9-Arylpolyhydroacridine in Water Catalyzed by Triethylbenzylammonium Chloride (TEBA)

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