Studies on the Synthesis and Bactericidal Activities of CatecholDiphenyl Ethers

Chinese Journal of Organic Chemistry ›› 2004, Vol. 24 ›› Issue (8): 927-932. Previous Articles Next Articles

邻苯二酚双苯醚的合成与抑菌活性研究

马梦林^a,b, 辛莹^a, 王玉良^*,a, 苟绍华^a, 陈淑华^*,a

^a四川大学化学学院成都 610064
^b西华大学化学系成都 611930

收稿日期:2003-10-14 修回日期:2004-01-12 接受日期:2004-03-10 发布日期:2022-09-20
通讯作者: * E-mail: chemchensh@sina.com
基金资助:
四川省教育厅青年基金(No. 2003B046)资助项目.

Studies on the Synthesis and Bactericidal Activities of CatecholDiphenyl Ethers

MA Meng-Lin^a,b, XIN Ying^a, WANG Yu-Liang^*,a, GOU Shao-Hua^a, CHEN Shu-Hua^*,a

^aCollege of Chemistry, Sichuan University, Chendu 610064
^bDepartment of Chemistry, Xihua University, Chendu 611930

Received:2003-10-14 Revised:2004-01-12 Accepted:2004-03-10 Published:2022-09-20

Abstract

Six halogenated nitro catechol diphenyl ethers were synthesized by the reaction of hydroxy-diphenyl ethers with chloro-nitrobenzene. Followed by reduction and diazotization-hydrolyzation, six halogenated amino catecholdiphenyl ethers and six halogenated hydroxyl catechol diphenyl ethers were obtained. The nitro and amino compounds have no bactericidal activities. Yet the hydroxyl compounds have good antimicrobial on the grampositive-bacteria and gramnegative-bacteria.

Key words: halogenated catechol diphenyl ether, synthesis, bactericidal activity

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MA Meng-Lin, XIN Ying, WANG Yu-Liang, GOU Shao-Hua, CHEN Shu-Hua. Studies on the Synthesis and Bactericidal Activities of CatecholDiphenyl Ethers[J]. Chinese Journal of Organic Chemistry, 2004, 24(8): 927-932.

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邻苯二酚双苯醚的合成与抑菌活性研究

Studies on the Synthesis and Bactericidal Activities of CatecholDiphenyl Ethers

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