Synthesis and Antimicrobial Activity of 2-(2'-Substituted hydra-zono)-1,3-dithiacyclopentane Derivatives

Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (03): 327-331. Previous Articles Next Articles

Reports

新型2-(2'-取代亚肼基)-1,3-二硫杂环戊烷衍生物的合成和菌活性研究

朱小康¹，陈洪超*^,1，王玉良¹，苟绍华¹
姜曼¹，杨志荣²，向明²

(¹四川大学化学学院成都 610064)
(²四川大学生命科学院成都 610064 )

收稿日期:2004-04-27 修回日期:2004-09-17 发布日期:2005-02-28
通讯作者: 陈洪超

Synthesis and Antimicrobial Activity of 2-(2'-Substituted hydra-zono)-1,3-dithiacyclopentane Derivatives

ZHU Xiao-Kang¹,CHEN Hong-Chao*^,1,WANG Yu-Liang¹,GOU Shao-Hua¹
JIANG Man¹,YANG Zhi-Rong²,XIANG Ming²

(¹ Faculty of Chemistry, Sichuan University, Chengdu 610064)
(² Faculty of Life Science, Sichuan University, Chengdu 610064)

Received:2004-04-27 Revised:2004-09-17 Published:2005-02-28
Contact: CHEN Hong-Chao

Abstract

Eleven 2-(2'-substituted hydrazono)-1,3-dithiacyclopentane derivatives have been designed and synthesized. Their structures have been confirmed by ¹H NMR, MS, IR spectra and elemental analysis. The antimicrobial test showed that the compounds possess a good antimicrobial activity on the testing bacterium and more expansive antimicrobial activity than tricyclazole and thiophanate-methyl (on sale). Among these, 4c has good antimicrobial activity on S. aureus, E. coli, S. ligneres, P. Vulgaris and D. cata.

Key words: 2-(2'-substituted hydrazono)-1,3-dithiacyclopentane, antimicrobial activ-ity, synthesis

Cite this article

ZHU Xiao-Kang,CHEN Hong-Chao*^,1,WANG Yu-Liang,GOU Shao-Hua
JIANG Man,YANG Zhi-Rong²,XIANG Ming². Synthesis and Antimicrobial Activity of 2-(2'-Substituted hydra-zono)-1,3-dithiacyclopentane Derivatives[J]. Chin. J. Org. Chem., 2005, 25(03): 327-331.

Export EndNote|Reference Manager|ProCite|BibTeX|RefWorks

[1]	Fakai Zou, Nengzhong Wang, Hui Yao, Hui Wang, Mingguo Liu, Nianyu Huang. Regio- and Stereo-selective Synthesis of 1β-/3R-Aryl Thiosugar [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 593-604.
[2]	Luyao Li, Zhongwen He, Zhenguo Zhang, Zhenhua Jia, Teck-Peng Loh. Application of Triaryl Carbenium in Organic Synthesis [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 421-437.
[3]	Qinggang Mei, Qinghan Li. Recent Progress of Visible Light-Induced the Synthesis of C(3) (Hetero)arylthio Indole Compounds [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 398-408.
[4]	Penghui Li, Qingyang Xie, Fuxian Wan, Yuanhong Zhang, Lin Jiang. Synthesis and Fungicidal Activity of Novel Substituted Pyrimidine-5-carboxamides Bearing Cyclopropyl Moiety [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 650-656.
[5]	Weiqing Yang, Yanbing Ge, Yuanyuan Chen, Ping Liu, Haiyan Fu, Menglin Ma. Design and Synthesis of Fluorescent 1,8-Napthalimide Derivatives and Their Identification of Cysteine [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 180-194.
[6]	Qianfan Zhao, Yongzheng Chen, Shiming Zhang. Application and Mechanism Study of Carbon-Based Metal-Free Catalysts in Organic Synthesis [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 137-147.
[7]	Shan Chen, Zhilin Chen, Qiong Hu, Yanshuang Meng, Yue Huang, Pingfang Tao, Liru Lu, Guobao Huang. Recognition of Bis-thiourea Tweezers to Neutral Molecules in Non-Polar Solvent [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 277-281.
[8]	Huakun Wang, Xiaolong Ren, Yining Xuan. Study of the Halide Salt Catalyzed [3＋2] Cycloaddition of α,β-Epoxy Carboxylate with Isocyanate [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 251-258.
[9]	Yukun Jin, Baoyi Ren, Fushun Liang. Visible Light-Mediated Selective C—F Bond Cleavage of Trifluoromethyl Groups and Its Application in Synthesizing gem-Difluoro-Containing Compounds [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 85-110.
[10]	Cuiyun Ma, Hailan Luo, Fuhua Zhang, Dan Guo, Shuxing Chen, Fei Wang. Green Biosynthesis, Photophysical Properties and Application of 3-Pyrrolyl BODIPY [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 216-223.
[11]	Bozhen Wang, Jie Zhang, Chunhui Nian, Mingming Jin, Miaomiao Kong, Wulan Li, Wenfei He, Jianzhang Wu. Synthesis and Antitumor Activity of 3,4-Dichlorophenyl Amides [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 232-241.
[12]	Shihang Yu, Jiawei Liu, Biyu An, Qinghua Bian, Min Wang, Jiangchun Zhong. Asymmetric Synthesis of the Contact Sex Pheromone of Neoclytus acuminatus acuminatus (Fabricius) [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 301-308.
[13]	Yang Li, Jinding Yuan, Di Zhao. Deep Eutectic Solvent of 1,3-Dimethylurea/L-(+)-Tartaric Acid for the Green Synthesis of (E)-2-Styrylquinoline-3-carboxylic Acid Derivatives [J]. Chinese Journal of Organic Chemistry, 2023, 43(9): 3268-3276.
[14]	Dandan Sui, Nannan Cen, Ruoqu Gong, Yang Chen, Wenbo Chen. Supporting-Electrolyte-Free Electrochemical Synthesis of Trifluoromethylated Oxindoles in Continuous Flow [J]. Chinese Journal of Organic Chemistry, 2023, 43(9): 3239-3245.
[15]	Ruixia Cao, Yuping Jia. Synthesis and Biological Activity of Novel Pyrrolo[2,3-d]pyrimidine Derivatives Containing Coumarin [J]. Chinese Journal of Organic Chemistry, 2023, 43(9): 3304-3311.

新型2-(2'-取代亚肼基)-1,3-二硫杂环戊烷衍生物的合成和菌活性研究

Synthesis and Antimicrobial Activity of 2-(2'-Substituted hydra-zono)-1,3-dithiacyclopentane Derivatives

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments