A novel type of chiral molecular tweezers has been designed and synthesized by using heteroaromatics as spacer and chiral unsymmetrical urea as arm. Their structures were identified by ¹H NMR, IR, MS spectra and elemental analysis. The recognition properties of these new receptors for halide anions have been investigated by UV-visible spectral titration. The preliminary results showed that all these molecular tweezers possessed the ability to form complex with anion examined. The greatest association constant reached 14270 L•mol^－1.

Key words: chiral unsymmetrical urea, synthesis, molecular tweezer, heteroaromatic