Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (9): 1142-1146. Previous Articles     Next Articles

Reports

新型异噻唑啉酮化合物的合成和抑菌活性研究

张佩玉1,2,喻秀1,陈智勇1,王玉良*,1
陈淑华1,杨志荣3,侯若彤3   

  1. (1四川大学化学学院 成都 610064)
    (2吐哈石油勘探开发指挥部钻采院 哈密 839009)
    (3四川大学生命科学院 成都 610064)
  • 收稿日期:2004-11-30 修回日期:2005-04-12 发布日期:2005-08-24
  • 通讯作者: 王玉良

Synthesis and the Antimicrobial Activity of New Isothiazolone Derivatives

ZHANG Pei-Yu1,2,YU Xiu1,CHEN Zhi-Yong1,WANG Yu-Liang*,1
CHEN Shu-Hua1,YANG Zhi-Rong3,HOU Ruo-Tong3   

  1. (1 The Faculty of Chemistry, Sichuan University, Chengdu 610064)
    (2 Tuha Institute of Petroleum Drilling and Production Technology, Hami 839009)
    (3 The Faculty of Life Science, Sichuan University, Chengdu 610064)
  • Received:2004-11-30 Revised:2005-04-12 Published:2005-08-24
  • Contact: WANG Yu-Liang

Ten 2-substituted isothiazolone derivatives have been synthesized. Seven of them were reported for the first time and their structures have been confirmed by 1H NMR, MS, IR spectra and elemental analysis. The antimicrobial test showed that the compounds possessed a good antimicrobial activity on the testing bacterium.

Key words: synthesis, isothiazolone, antimicrobial activity