Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (03): 271-281.     Next Articles

Review

“链接”化学及其应用

董卫莉,赵卫光*,李玉新,刘征骁,李正名   

  1. (南开大学元素有机化学国家重点实验室 元素有机化学研究所 天津 300071)
  • 收稿日期:2005-02-01 修回日期:2005-07-18 发布日期:2006-02-28
  • 通讯作者: 赵卫光

Click Chemistry and Its Applications

DONG Wei-Li,ZHAO Wei-Guang*,LI Yu-Xin,LIU Zheng-Xiao,LI Zheng-Ming   

  1. (National Key Laboratory of Elemento-organic Chemistry, Institute of Elemento-organic Chemistry,
    Nankai University, Tianjin 300071)
  • Received:2005-02-01 Revised:2005-07-18 Published:2006-02-28
  • Contact: ZHAO Wei-Guang

n this review, the basic concept of click chemistry, as a new synthetic method, is introduced with its applications to lead discovery, optimization, proteomics and DNA research in recent years.

Key words: synthesis, drug research, combinatorial chemistry, click chemistry