Synthesis and Biological Activity of N-(Substi-tuted-p-trifluoromethyl-phenyl)-1,3,5-trisubstituted-pyrazole-4-carboxamide Derivatives

Abstract

In order to find novel fungicides with high activity and low toxicity, ten new N-(substituted-p- trifluoromethylphenyl)-1,3,5-trisubstituted-pyrazole-4-carboxamide de-rivatives were synthesized. Their structures were characterized by IR, ¹H NMR spectra and elemental analysis. Preliminary bioassays indicated that some compounds showed fungicidal activity against Rhizoctonia sasakii, Gibberella zeae, Fusariun oxysporum, Phytophthora in-festans

Key words: fungicidal activity, synthesis, p-trifluoromethyl-phenylamine, pyrazolecarboxamide

Cite this article

DUHai-Tang^1,2,OUYANG Gui-Ping*^,1,DU Hai-Jun,SHI Da-Bin,JIN Lin-Hong^{a. Synthesis and Biological Activity of N-(Substi-tuted-p-trifluoromethyl-phenyl)-1,3,5-trisubstituted-pyrazole-4-carboxamide Derivatives[J]. Chin. J. Org. Chem., 2006, 26(03): 383-386.}

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N-(取代)对三氟甲基苯基-1,3,5-三取代吡唑-4-酰胺衍生物的合成与生物活性