Halo-1,3-butadiene derivatives are a series of important building blocks in organic synthesis, especially in the construction of cyclic compounds. Synthetic methods of halo 1,3-butadiene derivatives have attracted more and more attention for the potential applications in functional materials and organic synthesis. The development of synthetic methodologies of halo 1,3-butadienes is briefly reviewed.

Key words: halogenation reaction, synthesis, halo 1,3-butadiene derivative