Synthesis and Biological Activity of N-(5-Mercapto-1,3,4-thiadiazol-2- yl)-N'-(un)substituted Benzoylureas and (Un)substituted Phenoxyacetylureas

Abstract

Twenty-one new (un)substituted benzoylureas and (un)substituted phenoxyacetylureas have been synthesized by the reaction of 2-amino-5-mercapto-1,3,4-thiadiazole with (un)substituted benzoyl isocy-anates and (un)substituted phenoxyacetyl isocyanates, respectively, and their structures were confirmed by IR, ¹H NMR spectra and elemental analysis. The preliminary biological activity tests showed that some of the title compounds had good activity as plant growth regulators.

Key words: (un)substituted phenoxyacetylurea, 1,3,4-thiadiazole, biological activity, synthesis, (us)subsitituted benzoylurea

Cite this article

CHEN Chuan-Bing,b,ZHANG Zheng-Wen^a,DU Min^a
WANG Sheng^a,WANG Yan-Gang*^,a. Synthesis and Biological Activity of N-(5-Mercapto-1,3,4-thiadiazol-2- yl)-N'-(un)substituted Benzoylureas and (Un)substituted Phenoxyacetylureas[J]. Chin. J. Org. Chem., 2007, 27(11): 1444-1447.

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