Study on the Synthesis and Bactericidal Activities of New Brominated Hydroxy Diphenyl Ether

Abstract

Ten new brominated hydroxy diphenyl ethers have been designed and synthesized via etherification of phenols with para-hydroxyphenyl chloride and bromination of the formed diphenyl ethers. Their structures have been confirmed by ¹H NMR, IR, mass spectra and elemental analysis. These new compounds will not generate dioxins during their manufacture and use. The bioactivity test showed that these compounds possessed good antimicrobial activities toward the tested bacteria.

Key words: synthesis, brominated 4-hydroxy diphenyl ether, antimicrobial activity

Cite this article

ZOU Yan^a, WU Jie^c, HOU Ruo-Tong^b, WU Kai-Qun*^,a, WANG Yu-Liang^a
CHEN Shu-Hua^a, YANG Zhi-Rong^bsup>a, WANG Yu-Zhong<. Study on the Synthesis and Bactericidal Activities of New Brominated Hydroxy Diphenyl Ether[J]. Chin. J. Org. Chem., 2008, 28(01): 111-114.

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