Synthesis and Biological Activity of 1,3,4-Triazolo[2,1-b]- 1,3,4-thiadiazole Derivatives

Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (07): 1199-1203. Previous Articles Next Articles

Original Articles

1,3,4-均三唑并[2,1-b]-1,3,4-噻二唑衍生物的合成及生物活性

柴安; 薛思佳*; 卞王东 ; 吁松瑞

(上海师范大学化学系上海 200234)

收稿日期:2007-11-13 修回日期:2007-12-24 发布日期:2008-07-28
通讯作者: 薛思佳

Synthesis and Biological Activity of 1,3,4-Triazolo[2,1-b]- 1,3,4-thiadiazole Derivatives

CHAI, An; XUE, Si-Jia*; BIAN, Wang-Dong ; YU, Song-Rui

(Department of Chemistry, Shanghai Normal University, Shanghai 200234)

Received:2007-11-13 Revised:2007-12-24 Published:2008-07-28
Contact: XUE, Si-Jia

Abstract

Ten unreported compounds 5-(p-tolyl)-2-(substituted phenoxyacetamido)-s-triazolo[2,1-b]- 1,3,4-thiadiazoles were synthesized by the reaction of 5-(p-tolyl)-1-amino-2-mercapto-1,3,4-triazole with substituted phenoxyacetyl isothiocyanates, their structures were elucidated and confirmed by elemental analysis, IR, 1H NMR and MS spectra, and preliminary biological test indicated that the compounds had good herbicidal activities.

Key words: synthesis, herbicidal activity, s-triazolo[2,1-b]-1,3,4-thiadiazole

Cite this article

CHAI, An; XUE, Si-Jia*; BIAN, Wang-Dong ; YU, Song-Rui. Synthesis and Biological Activity of 1,3,4-Triazolo[2,1-b]- 1,3,4-thiadiazole Derivatives[J]. Chin. J. Org. Chem., 2008, 28(07): 1199-1203.

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1,3,4-均三唑并[2,1-b]-1,3,4-噻二唑衍生物的合成及生物活性

Synthesis and Biological Activity of 1,3,4-Triazolo[2,1-b]- 1,3,4-thiadiazole Derivatives

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