Novel Synthesis of 2,6-Diamino-3,5-dinitropyridine-1-oxide

Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (11): 1943-1947. Previous Articles Next Articles

Original Articles

2,6-二氨基-3,5-二硝基吡啶-1-氧化物的合成新方法

成健^a ; 姚其正^b; 周新利^a; 杜扬^a; 方东^a; 刘祖亮^*,a

(a南京理工大学化工学院南京 210094)
(b中国药科大学药学院南京 210094)

收稿日期:2008-04-01 修回日期:2008-04-28 发布日期:2008-11-18
通讯作者: 刘祖亮

Novel Synthesis of 2,6-Diamino-3,5-dinitropyridine-1-oxide

CHENG, Jian ^a; YAO, Qi-Zheng ^b; ZHOU, Xin-Li ^a; DU, Yang ^a;
FANG, Dong ^a; LIU, Zu-Liang^*,a

(a School of Chemical Engineering, Nanjing University of Science & Technology, Nanjing 210094)
(b School of Pharmacy, China Pharmaceutical University, Nanjing 210094)

Received:2008-04-01 Revised:2008-04-28 Published:2008-11-18
Contact: LIU, Zu-Liang

Abstract

A novel synthetic method of 2,6-diamino-3,5-dinitropyridine-1-oxide (ANPyO) was explored using 2,6-diaminopyridine as the starting materials in three steps, including acetylation, N-oxidation and nitration. Thus, the overall yield of ANPyO was up to 75%. Detonation velocity, detonation pressure, DSC and sensitivities of electrospark and impact for ANPyO were measured, showing that ANPyO and 1,3,5-triamino-2,4,6-trinitrobenzene (TATB) are almost equal in overall performance.

Key words: 1,3,5-triamino-2,4,6-trinitrobenzene, 2,6-diamino-3,5-dinitropyridine-1-oxide, synthesis, performance

Cite this article

CHENG, Jian ^a; YAO, Qi-Zheng ^b; ZHOU, Xin-Li ^a; DU, Yang ^a;
FANG, Dong ^a; LIU, Zu-Liang^*,a
. Novel Synthesis of 2,6-Diamino-3,5-dinitropyridine-1-oxide[J]. Chin. J. Org. Chem., 2008, 28(11): 1943-1947.

Export EndNote|Reference Manager|ProCite|BibTeX|RefWorks

[1]	Fakai Zou, Nengzhong Wang, Hui Yao, Hui Wang, Mingguo Liu, Nianyu Huang. Regio- and Stereo-selective Synthesis of 1β-/3R-Aryl Thiosugar [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 593-604.
[2]	Luyao Li, Zhongwen He, Zhenguo Zhang, Zhenhua Jia, Teck-Peng Loh. Application of Triaryl Carbenium in Organic Synthesis [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 421-437.
[3]	Qinggang Mei, Qinghan Li. Recent Progress of Visible Light-Induced the Synthesis of C(3) (Hetero)arylthio Indole Compounds [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 398-408.
[4]	Penghui Li, Qingyang Xie, Fuxian Wan, Yuanhong Zhang, Lin Jiang. Synthesis and Fungicidal Activity of Novel Substituted Pyrimidine-5-carboxamides Bearing Cyclopropyl Moiety [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 650-656.
[5]	Weiqing Yang, Yanbing Ge, Yuanyuan Chen, Ping Liu, Haiyan Fu, Menglin Ma. Design and Synthesis of Fluorescent 1,8-Napthalimide Derivatives and Their Identification of Cysteine [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 180-194.
[6]	Qianfan Zhao, Yongzheng Chen, Shiming Zhang. Application and Mechanism Study of Carbon-Based Metal-Free Catalysts in Organic Synthesis [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 137-147.
[7]	Shan Chen, Zhilin Chen, Qiong Hu, Yanshuang Meng, Yue Huang, Pingfang Tao, Liru Lu, Guobao Huang. Recognition of Bis-thiourea Tweezers to Neutral Molecules in Non-Polar Solvent [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 277-281.
[8]	Huakun Wang, Xiaolong Ren, Yining Xuan. Study of the Halide Salt Catalyzed [3＋2] Cycloaddition of α,β-Epoxy Carboxylate with Isocyanate [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 251-258.
[9]	Yukun Jin, Baoyi Ren, Fushun Liang. Visible Light-Mediated Selective C—F Bond Cleavage of Trifluoromethyl Groups and Its Application in Synthesizing gem-Difluoro-Containing Compounds [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 85-110.
[10]	Cuiyun Ma, Hailan Luo, Fuhua Zhang, Dan Guo, Shuxing Chen, Fei Wang. Green Biosynthesis, Photophysical Properties and Application of 3-Pyrrolyl BODIPY [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 216-223.
[11]	Bozhen Wang, Jie Zhang, Chunhui Nian, Mingming Jin, Miaomiao Kong, Wulan Li, Wenfei He, Jianzhang Wu. Synthesis and Antitumor Activity of 3,4-Dichlorophenyl Amides [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 232-241.
[12]	Shihang Yu, Jiawei Liu, Biyu An, Qinghua Bian, Min Wang, Jiangchun Zhong. Asymmetric Synthesis of the Contact Sex Pheromone of Neoclytus acuminatus acuminatus (Fabricius) [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 301-308.
[13]	Ruixia Cao, Yuping Jia. Synthesis and Biological Activity of Novel Pyrrolo[2,3-d]pyrimidine Derivatives Containing Coumarin [J]. Chinese Journal of Organic Chemistry, 2023, 43(9): 3304-3311.
[14]	Huanqing Li, Zhaohua Chen, Zujia Chen, Qiwen Qiu, Youcai Zhang, Sihong Chen, Zhaoyang Wang. Research Progress in Mercury Ion Fluorescence Probes Based on Organic Small Molecules [J]. Chinese Journal of Organic Chemistry, 2023, 43(9): 3067-3077.
[15]	Ran Zhou, Chunmei Yuan, Tao Zhang, Piao Mao, Yi Liu, Kaini Meng, Hui Xin, Wei Xue. Design, Synthesis and Bioactivity of Chalcone Derivative Containing Quinazolinone [J]. Chinese Journal of Organic Chemistry, 2023, 43(9): 3196-3209.

2,6-二氨基-3,5-二硝基吡啶-1-氧化物的合成新方法

Novel Synthesis of 2,6-Diamino-3,5-dinitropyridine-1-oxide

PDF

Knowledge

Cited

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments