Synthesis and Biological Activity of Substituted 1,2,4-Triazolo[1,5-c]pyrimidine Derivatives

Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (02): 245-251. Previous Articles Next Articles

Original Articles

取代1,2,4-三唑并[1,5-c]嘧啶衍生物的合成与生物活性

陈超南 ; 陈琼*; 杨光富

(华中师范大学化学学院农药与化学生物学教育部重点实验室武汉 430079)

收稿日期:2008-02-28 修回日期:2008-05-29 发布日期:2009-02-20
通讯作者: 陈琼

Synthesis and Biological Activity of Substituted 1,2,4-Triazolo[1,5-c]pyrimidine Derivatives

Chen, Chaonan; Chen, Qiong*; Yang, Guangfu

(Key Laboratory of Pesticide & Chemical Biology, Education of Ministry, College of Chemistry,
Central China Normal University, Wuhan 430079, China)

Received:2008-02-28 Revised:2008-05-29 Published:2009-02-20
Contact: Chen, Qiong

Abstract

Sixteen novel 2-[substituted benzyloxy 7-chloro-5-methylsulfanyl-[1,2,4]-triazolo[1,5-c] pyrimidine derivatives and thirty-six novel substituted 2-phenoxy-[1,2,4]-triazolo[1,5-c]pyrimidine deriva- tives have been designed and synthesized using substituted 4-hydrazinopyrimidine as starting material. All synthesized compounds were confirmed by elemental analysis, MS and 1H NMR techniques. Preliminary bioassay indicates that some of them display good herbicidal and fungicidal activities.

Key words: synthesis, biological activity, 1,2,4-triazolo[1,5-c]pyrimidine

Cite this article

Chen, Chaonan; Chen, Qiong*; Yang, Guangfu. Synthesis and Biological Activity of Substituted 1,2,4-Triazolo[1,5-c]pyrimidine Derivatives[J]. Chin. J. Org. Chem., 2009, 29(02): 245-251.

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取代1,2,4-三唑并[1,5-c]嘧啶衍生物的合成与生物活性

Synthesis and Biological Activity of Substituted 1,2,4-Triazolo[1,5-c]pyrimidine Derivatives

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