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Chin. J. Org. Chem. ›› 2011, Vol. 31 ›› Issue (9): 1480-1483. Previous Articles     Next Articles

Notes

可能用于光动力诊疗的2-硝基咪唑卟啉衍生物的合成及表征

吴海霞1,2，沈鸣1，钱旭红*,1，徐玉芳1   

  1. (1华东理工大学药学院 上海市化学生物学重点实验室 上海 200237)
    (2兰州石化职业技术学院应用化学工程系 兰州 730060)
  • 收稿日期:2010-08-30 修回日期:2010-12-09 发布日期:2011-04-12
  • 通讯作者: 徐玉芳 E-mail:yfxu@ecust.edu.cn

Synthesis and Characterization of Potential Photodynamic Treatment with Porphyrin Derivatives Substituted with 2-Nitroimidazole

Wu Haixia1,2 Shen Yanming1 Qian Xu-hong*,1 Xu Yufang1   

  1. (1 Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science & Technology, Shanghai 200237)
    (2 Department of Applied Chemical Engineering, Lanzhou Vocational Technical College of Petrochemistry, Lanzhou 730060)
  • Received:2010-08-30 Revised:2010-12-09 Published:2011-04-12
  • Contact: Yu-fang Xu E-mail:yfxu@ecust.edu.cn

PDF

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Starting from pyrrole and 4-hydroxybenzaldehyde, four novel porphyrin derivatives substituted with 2-nitroimidazole were prepared. The structures of all the synthesized compounds were identified by UV-Vis, FT-IR, 1H NMR and HRMS techniques.

Key words: 2-nitroimidazole, porphyrin, synthesis, characterization