Synthesis and Biological Activity of Diheterocyclic 5,7-Dimethyl-1,2,4- triazolo[1,5-a]pyrimidine Derivatives

Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (11): 1965-1970. Previous Articles Next Articles

Original Articles

5,7-二甲基-1,2,4-三唑并[1,5-a]嘧啶双杂环衍生物的合成与生物活性

马忠华^a,b; 刘祖明^b; 陈琼^*,b

(a华中农业大学理学院武汉 430070)
(b华中师范大学农药与化学生物学教育部重点实验室武汉 430079)

收稿日期:2008-03-04 修回日期:2008-04-27 发布日期:2008-11-18
通讯作者: 陈琼

Synthesis and Biological Activity of Diheterocyclic 5,7-Dimethyl-1,2,4- triazolo[1,5-a]pyrimidine Derivatives

MA, Zhong-Hua ^a,b; LIU, Zu-Ming ^b; CHEN, Qiong^*,b

(a College of Basic Sciences, Huazhong Agricultural University, Wuhan 430070)
(b Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, College of Chemistry,
Central China Normal University, Wuhan 430079)

Received:2008-03-04 Revised:2008-04-27 Published:2008-11-18
Contact: CHEN, Qiong

Abstract

Seventeen novel diheterocyclic compounds containing 1,2,4-triazolo[1,5-a]pyrimidine and 1,2,4-triazole moieties were designed and synthesized by using 2-mercapto-5,7-dimethyl-1,2,4-triazolo[1,5-a]- pyrimidine as starting materials. All compounds obtained were confirmed by elemental analyses, MS, 1H NMR and 13C NMR spectra. Preliminary biological activity indicated that some of them displayed good fungicidal and her-bicidal activities.

Key words: 1,2,4-triazole, 1,2,4-triazolo[1,5-a]pyrimidine, synthesis, biological activi

Cite this article

MA, Zhong-Hua ^a,b; LIU, Zu-Ming ^b; CHEN, Qiong^*,b. Synthesis and Biological Activity of Diheterocyclic 5,7-Dimethyl-1,2,4- triazolo[1,5-a]pyrimidine Derivatives[J]. Chin. J. Org. Chem., 2008, 28(11): 1965-1970.

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5,7-二甲基-1,2,4-三唑并[1,5-a]嘧啶双杂环衍生物的合成与生物活性

Synthesis and Biological Activity of Diheterocyclic 5,7-Dimethyl-1,2,4- triazolo[1,5-a]pyrimidine Derivatives

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