Synthesis and Biological Activities of N-(5-Alkyl-2,4-dihydro-3-thioxo-1,2,4-triazol-4-yl) Schiff Bases

Abstract

Seven Schiff bases have been prepared by an acid catalyzed condensation of 5-alkyl-4-amino- 2,4-dihydro-1,2,4-triazole-3-thione with substituted aromatic aldehydes, the structures of which have been confirmed by ¹H NMR, IR spectra and elemental analysis. Their biological activities to several vegetable pathogens have been tested, showing that they exhibited good fungicidal activities.

Key words: 2,4-dihydro-1,2,4-triazole-3-thione, synthesis, Schiff base, biological activity

Cite this article

SUN Xiao-Hong*^,a, TAO Yan^a, LIU Yuan-Fa^b, JIA Ying-Qi^b
CHEN Bang^b, YANG Jian-Wu^a. Synthesis and Biological Activities of N-(5-Alkyl-2,4-dihydro-3-thioxo-1,2,4-triazol-4-yl) Schiff Bases[J]. Chin. J. Org. Chem., 2008, 28(01): 155-159.

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