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Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (10): 1306-1310. Previous Articles     Next Articles

Reports

N-[5-(1-邻(对)氯苯氧乙基)-1,3,4-噻二唑-2-基]-N'-芳酰基硫脲的合成与生物活性

王子云1,2，龚银香3，陈传兵1，宋新建1，汪焱钢*,1   

  1. (1华中师范大学化学学院 武汉 430079)
    (2周口师范学院化学系 周口 466000)
    (3长江大学化学与环境工程学院 荆州 434000)
  • 收稿日期:2005-01-19 修回日期:2005-04-28 发布日期:2005-10-08
  • 通讯作者: 汪焱钢

Synthesis and Biological Activity of N-[5-(1-o(p)-Chlorophenoxy- ethyl)-1,3,4-thiodiazol-2-yl]-N'-aroyl Thioureas

WANG Zi-Yun1,2,GONG Yin-Xiang3,CHEN Chuan-Bing1,SONG Xin-Jian1 WANG Yan-Gang*,1   

  1. (1 College of Chemistry, Central China Normal University, Wuhan 430079)
    (2 Department of Chemistry, Zhoukou Normal University, Zhoukou 466000)
    (3 College of Chemistry and Environmental Engineering, Yangtze Univer-sity, Jingzhou 434000)
  • Received:2005-01-19 Revised:2005-04-28 Published:2005-10-08
  • Contact: WANG Yan-Gang

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In order to find high active pesticide containing heterocycle, twenty-six novel aroyl thioureas have been synthesized by the reaction of 2-amino-5-[1-o(p)-chlorophenoxyethyl]-1,3,4-thiodiazole with aroyl isothiocyanates. Their structures were confirmed by 1H NMR, IR spectra and elemental analysis. The preliminary biological activity tests showed that some title compounds have good activities as plant growth regulator and 3c, 3d, 3e, 4b and 4c have excellent activity of auxin.

Key words: aroyl thiourea, synthesis, 1,3,4-thiodiazole, auxin, biological activity