Chin. J. Org. Chem. ›› 1995, Vol. 15 ›› Issue (1): 67-71. Previous Articles     Next Articles

Original Articles

(R)-2-硫代四氢噻唑-4-羧酸及其酯的合成

黄化民;李叶芝;胡学山;田庆宇;郎美东;李惟;王玉宏   

  1. 吉林大学化学系;吉林大学分子生物学系
  • 发布日期:1995-02-25

Synthesis of (R)-2-thioxothiazolidine-4-carboxylic acid and its esters

HUANG HUAMIN;LI YEZHI;HU XUESHAN;TIAN QINGYU;LANG MEIDONG;LI WEI;WANG YUHONG   

  • Published:1995-02-25

(R)-2-Thioxothiazolidine-4-carboxylic acid was stereospecifically prepared from L-cysteine hydrochloride monohdrate and carbodisulfide in aqueous sodium hydroxide and Lead nitrate. Under Catalization of Fe~2(SO~4)~3·XH~2O a series of chiral esters of (R)-2-thioxothiazolidine-4-carboxylic acid were synthesized by direct esterification of the acid with alcohols.

Key words: REACTION KINETICS FOR THE ESTERIFICATION, SYNTHESIS

CLC Number: