Synthesis and Herbicidal Activity of 4-Pyrazolyl-2-aryloxypyrimidine Derivatives

Abstract

In order to search for novel compounds with herbicidal activity, a series of 4-pyrazolyl- 2-aryloxypyrimidine derivatives were designed and synthesized using 2,4-dichloropyrimidine as a starting material. All compounds synthesized were confirmed by ¹H NMR and elementary analysis. Preliminary bioassay results indicated that some compounds display herbicidal activity. For example, compound 5c exhibit igher than 80% inhibition activity against rape and barnyard grass in dosage of 100 μg•mL^－1.

Key words: pyrazole, synthesis, herbicidal activity, pyrimidine

Cite this article

LIU Wei-Min,ZOU Xiao-Mao,SONG Hong-Hai,WANG Yi-Feng
ZHU You-Quan,YANG Hua-Zheng*. Synthesis and Herbicidal Activity of 4-Pyrazolyl-2-aryloxypyrimidine Derivatives[J]. Chin. J. Org. Chem., 2006, 26(11): 1600-1605.

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