-(4-Carboxyphenyl)-10,15,20-triphenylporphyrin and 5-(4-hydroxyphenyl)-10,15,20-triphenyl- porphyrin were used as starting materials to react with ethyl N-(Boc-aminoethyl)glycinate (3) and its derivative 4 respectively to yield two peptide nucleic acid monomeric backbone bonded porphyrin compounds 6 and 8. These new compounds were confirmed by absorption spectroscopy, ¹H NMR, MS and elemental analysis. The fluorescence spectroscopic properties of the target compounds were studied, and there were no evident changes of fluorescence wavelength and intensity when peptide nucleic acid monomeric backbone was bonded to porphyrin ring.

Key words: porphyrin, synthesis, fluorescence, peptide nucleic acid