Study on the Synthesis and Biological Activity of Schiff Bases of 3-Amino-dihydrothiophene-2-one

Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (01): 82-86. Previous Articles Next Articles

Original Articles

3-氨基-二氢噻吩-2-酮类Schiff碱的合成和生物活性研究

孙晓红*^,a，李淑娟^a，刘源发^b，陈邦^b
贾婴琦^b，陶燕^a

(^a西北大学化学研究所西安 710069)
(^b西北大学化学系西安 710069)

收稿日期:2006-03-04 修回日期:1900-01-01 发布日期:2006-12-30
通讯作者: 孙晓红

Study on the Synthesis and Biological Activity of Schiff Bases of 3-Amino-dihydrothiophene-2-one

SUN Xiao-Hong*^,a,LI Shu-Juan^a,LIU Yuan-Fa^b,CHEN Bang^b
JIA Ying-Qi^b,TAO Yan^a

(^a Chemical Institute, Northwest University, Xi′an 710069)
(^b Department of Chemistry, Northwest University, Xi′an 710069)

Received:2006-03-04 Revised:1900-01-01 Published:2006-12-30
Contact: SUN Xiao-Hong

Abstract

Nine Schiff bases of 3-amino-dihydrothiophene-2-one were synthesized by reaction of substituted benzaldehyde with DL-homocysteine thiolactone hydrochloride by means of preferable reaction conditions. Seven of them were reported for the first time. The structures of the compounds were confirmed by elemental analysis, ¹H NMR and IR spectra. The biological tests showed that they were excellent biological active to several vegetable pathogen.

Key words: Schiff base, synthesis, biological activity, 3-amino-dihydrothiophene-2-one

Cite this article

SUN Xiao-Hong*^,a,LI Shu-Juan^a,LIU Yuan-Fa^b,CHEN Bang^b
JIA Ying-Qi^b,TAO Yan^a. Study on the Synthesis and Biological Activity of Schiff Bases of 3-Amino-dihydrothiophene-2-one[J]. Chin. J. Org. Chem., 2007, 27(01): 82-86.

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3-氨基-二氢噻吩-2-酮类Schiff碱的合成和生物活性研究

Study on the Synthesis and Biological Activity of Schiff Bases of 3-Amino-dihydrothiophene-2-one

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