Synthesis of Bis(indol-3-yl)methanes Catalyzed by Montmorillonite K10-ZnCl2 by Grinding

Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (07): 1238-1242. Previous Articles Next Articles

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蒙脱土K10-ZnCl2催化下研磨法合成二吲哚甲烷衍生物

李记太* ; 蔺志平

(河北大学化学与环境科学学院河北省分析科学技术重点实验室保定 071002)

收稿日期:2007-11-18 修回日期:2007-12-17 发布日期:2008-07-28
通讯作者: 李记太

Synthesis of Bis(indol-3-yl)methanes Catalyzed by Montmorillonite K10-ZnCl2 by Grinding

LI, Ji-Tai* ; LIN, Zhi-Ping

(Hebei Key Laboratory of Analytical Science and Technology, College of Chemistry and Environmental Science,
Hebei University, Baoding 071002)

Received:2007-11-18 Revised:2007-12-17 Published:2008-07-28
Contact: LI, Ji-Tai

Abstract

Montmorillonite K10-supported _^ZnCl2is an efficient and environmentally friendly catalyst. Reactions of aromatic aldehydes with indole catalyzed by montmorillonite K10-ZnCl2 afforded bis(indol-3-yl)- methanes in 66%～97% yields within 2～8 min by grinding. This method provided several advantages such as simple work-up procedure, shorter reaction time, milder conditions and environmental friendliness.

Key words: montmorillonite K10-ZnCl2, bis(indol-3-yl)methane, synthesis, grinding

Cite this article

LI, Ji-Tai* ; LIN, Zhi-Ping. Synthesis of Bis(indol-3-yl)methanes Catalyzed by Montmorillonite K10-ZnCl2 by Grinding[J]. Chin. J. Org. Chem., 2008, 28(07): 1238-1242.

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蒙脱土K10-ZnCl2催化下研磨法合成二吲哚甲烷衍生物

Synthesis of Bis(indol-3-yl)methanes Catalyzed by Montmorillonite K10-ZnCl2 by Grinding

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