Synthesis and Characterization of 2-Substituted-5-(perchloropyridin- 2-yl)-1,3,4-oxadiazolines Derivatives

Chin. J. Org. Chem. ›› 2010, Vol. 30 ›› Issue (10): 1535-1538. Previous Articles Next Articles

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2-取代-5-(全氯吡啶-2-基)-1,3,4-噁二唑啉的合成及表征

沈芬芳，徐丽娟，强根荣，宋庆宝

(浙江工业大学绿色化学合成技术国家重点实验室培育基地杭州 310014)

收稿日期:2009-11-13 修回日期:2010-04-25 发布日期:2010-05-06
通讯作者: 宋庆宝 E-mail:qbsong@zjut.edu.cn
基金资助:
浙江省重中之重学科开放基金和绿色化学合成技术国家重点实验室培育基地开放基金资助项目

Synthesis and Characterization of 2-Substituted-5-(perchloropyridin- 2-yl)-1,3,4-oxadiazolines Derivatives

SHEN Fen-Fang, XU Li-Juan, QIANG Gen-Rong, SONG Qing-Bao

(State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, Zhejiang University of Technology, Hangzhou 310014)

Received:2009-11-13 Revised:2010-04-25 Published:2010-05-06

Abstract

The perchloronictinic hydrazine has been prepared using esterification and hydrazinolysis of perchloropyridin-2-carboxylic acid, and then condensated with aldehydes (ketones) producing correspond hydrazones. Finally 2-substituted-5-(perchloropyridin-2-yl)-1,3,4-oxadiazolines have been obtained by the cyclodehydration of these hydrazones in acetic anhydride. Their molecule structures were characterized by elemental analysis,IR, ¹H NMR, ¹³C NMR and MS techniques.

Key words: oxadiazoline, perchloropyridin-2-carboxylic acid, hydrazone, synthesis

Cite this article

SHEN Fen-Fang, XU Li-Juan, QIANG Gen-Rong, SONG Qing-Bao. Synthesis and Characterization of 2-Substituted-5-(perchloropyridin- 2-yl)-1,3,4-oxadiazolines Derivatives[J]. Chin. J. Org. Chem., 2010, 30(10): 1535-1538.

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2-取代-5-(全氯吡啶-2-基)-1,3,4-噁二唑啉的合成及表征

Synthesis and Characterization of 2-Substituted-5-(perchloropyridin- 2-yl)-1,3,4-oxadiazolines Derivatives

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