Chin. J. Org. Chem. ›› 2011, Vol. 31 ›› Issue (05): 752-756. Previous Articles     Next Articles

Notes

碱性离子液体催化下一锅三组分合成螺环吲哚衍生物

郭红云*,田金金   

  1. (浙江工业大学化学工程与材料学院 杭州 310014)
  • 收稿日期:2010-06-23 修回日期:2010-11-23 发布日期:2010-12-27
  • 通讯作者: 郭红云 E-mail:guohy63@163.com

One-Pot Three-Component Synthesis of Spirooxindoles Catalyzed by Basic Ionic Liquids

GUO Hong-Yun, TIAN Jin-Jin   

  1. (College of Chemical Engineering and Material Science, Zhejiang University of Technology, Hangzhou 310014)
  • Received:2010-06-23 Revised:2010-11-23 Published:2010-12-27

A series of spirooxindoles were synthesized by a three component, one pot condensation of isatin, malononitrile/ethyl cyanoacetate and β-diketone using [H3NCH2CH2OH][CH3COO] as a basic ionic liq-uid catalyst. The products were identified by 1H NMR, IR and MS techniques. This method has some distinct advantages such as mild reaction conditions, short reaction time, environmental friendliness and accessibility of catalyst.

Key words: basic ionic liquid, one pot, three component, spirooxindole