Base Promoted Annulation of Carbodiimides to Access of Quinazoline and Their Derivatives

doi:10.6023/cjoc201607010

Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (3): 746-752.DOI: 10.6023/cjoc201607010 Previous Articles Next Articles

Notes

碱促进下碳二亚胺参与构建二氢喹唑啉及其衍生物

汤玲娟^a,b, 陆新谋^b, 纪顺俊^b

a 南通大学分析测试中心南通 226019;
b 江苏省有机合成重点实验室苏州大学材料与化学化工学部苏州 215123

收稿日期:2016-07-05 修回日期:2016-10-19 发布日期:2016-12-12
通讯作者: 纪顺俊,E-mail:shunjun@suda.edu.cn E-mail:shunjun@suda.edu.cn
基金资助:
国家自科学然基金（No.21372174）、江苏省高校优势学科建设工程资助项目.

Base Promoted Annulation of Carbodiimides to Access of Quinazoline and Their Derivatives

Tang Lingjuan^a,b, Lu Xinmou^b, Ji Shunjun^b

a Analysis and Testing Center, Nantong University, Suzhou 226019;
b Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123

Received:2016-07-05 Revised:2016-10-19 Published:2016-12-12
Contact: 10.6023/cjoc201607010 E-mail:shunjun@suda.edu.cn
Supported by:
Project supported by the National Natural Science Foundation of China (Nos. 21372174, 21542015), the Priority Academic Program Development of Jiangsu Higher Education Institutions.

1. Base Promoted Annulation of Carbodiimides to Access of Quinazoline and Their Derivatives.PDF(1410KB)

Abstract

An efficient methodology to access of quinazoline derivatives by the reaction of carbodiimides and alcohol under basic conditions has been developed. This paper provides an attractive strategy for construction of the quinazoline compounds and other heterocyclic compounds in a high reaction yield by using simple starting materials in mild reaction conditions and short reaction time.

Key words: carbodiimides, α,β-unsaturated ketone, quinazoline and their derivatives, metal-free

Cite this article

Tang Lingjuan, Lu Xinmou, Ji Shunjun. Base Promoted Annulation of Carbodiimides to Access of Quinazoline and Their Derivatives[J]. Chin. J. Org. Chem., 2017, 37(3): 746-752.

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碱促进下碳二亚胺参与构建二氢喹唑啉及其衍生物

Base Promoted Annulation of Carbodiimides to Access of Quinazoline and Their Derivatives

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