Synthesis,Herbicidal Activities of Novel Triketone Compounds Containing 4-Substituted Cyclopentane-1,3-dione Moiety

doi:10.6023/cjoc201704039

Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (10): 2717-2724.DOI: 10.6023/cjoc201704039 Previous Articles Next Articles

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新型含4-取代-1,3-环戊二酮结构的三酮类化合物的合成与除草活性研究

徐海珍^a, 谢丽芬^b, 韩廷锋^b, 何敬立^b, 朱有全^b

a 天津师范大学化学学院天津 300387;
b 南开大学化学学院元素有机化学国家重点实验室天津 300071

收稿日期:2017-04-24 修回日期:2017-05-10 发布日期:2017-06-07
通讯作者: 徐海珍, 朱有全 E-mail:hxxyxhz@mail.tjnu.edu.cn;zyq8165@nankai.edu.cn
基金资助:
国家自然科学基金（Nos.21072108，21372134）资助项目.

Synthesis,Herbicidal Activities of Novel Triketone Compounds Containing 4-Substituted Cyclopentane-1,3-dione Moiety

Xu Haizhen^a, Xie Lifen^b, Han Tingfeng^b, He Jingli^b, Zhu Youquan^b

a College of Chemistry, Tianjin Normal University, Tianjin 300387;
b State Key Laboratory of Elemento-organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071

Received:2017-04-24 Revised:2017-05-10 Published:2017-06-07
Contact: 10.6023/cjoc201704039 E-mail:hxxyxhz@mail.tjnu.edu.cn;zyq8165@nankai.edu.cn
Supported by:
Project supported by the National Natural Science Foundation of China (Nos.21072108,21372134).

1. Synthesis,Herbicidal Activities of Novel Triketone Compounds Containing 4-Substituted Cyclopentane-1,3-dione Moiety.PDF(1111KB)

Abstract

To find new lead compounds with muti-bioactivities, a series of novel triketone derivatives containing 4-substituted cyclopentane-1,3-dione were designed on the base of various commercial products. The target compounds were synthesized from cyclopentane-1,3-dione in six steps. Their structures were confirmed by IR, ¹H NMR spectra and HRMS. The preliminary greenhouse bioassay results indicated that some compounds showed obvious inhibition effects against Brassica campestris, and the inhibition rate was more than 80% at 100 μg/mL. In the pre-and post-emergence, some of them exhibited excellent herbicidal activities against Brassica campestris, and the herbicidal activity was more than 90% at 1500 g/ha.

Key words: triketone, 4-substituted cyclopentane-1,3-dione, synthesis, herbicidal activity

Cite this article

Xu Haizhen, Xie Lifen, Han Tingfeng, He Jingli, Zhu Youquan. Synthesis,Herbicidal Activities of Novel Triketone Compounds Containing 4-Substituted Cyclopentane-1,3-dione Moiety[J]. Chin. J. Org. Chem., 2017, 37(10): 2717-2724.

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新型含4-取代-1,3-环戊二酮结构的三酮类化合物的合成与除草活性研究

Synthesis,Herbicidal Activities of Novel Triketone Compounds Containing 4-Substituted Cyclopentane-1,3-dione Moiety

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