Study on Allylation Reactions of Trifluoromethylated Acylhydrazones with Allylsilanes or Allylboronates

doi:10.6023/cjoc201912006

Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (6): 1689-1696.DOI: 10.6023/cjoc201912006 Previous Articles Next Articles

Special Issue: 有机硅化学虚拟合辑

三氟甲基酰腙与烯丙基硅或烯丙基硼试剂的烯丙基化反应研究

虎永琴, 黄丹凤, 王克虎, 赵转霞, 赵芳霞, 徐炜刚, 胡雨来

西北师范大学化学化工学院兰州 730070

收稿日期:2019-12-04 修回日期:2020-02-17 发布日期:2020-03-04
通讯作者: 黄丹凤, 胡雨来 E-mail:huyl@nwnu.edu.cn;huangdf@nwnu.edu.cn
基金资助:
国家自然科学基金（No.21662030）资助项目.

Study on Allylation Reactions of Trifluoromethylated Acylhydrazones with Allylsilanes or Allylboronates

Hu Yongqin, Huang Danfeng, Wang Kehu, Zhao Zhuanxia, Zhao Fangxia, Xu Weigang, Hu Yulai

College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070

Received:2019-12-04 Revised:2020-02-17 Published:2020-03-04
Supported by:
Project supported by the National Natural Science Foundation of China (No. 21662030).

1. 201689S.pdf(3909KB)

Abstract

Allylation reactions of trifluoromethylated acylhydrazones with allyltrimethylsilane or pinacolyl allylboronate were found to proceed smoothly in the presence of Lewis acid to afford a series of trifluoromethylated homoallylic N-acylhydrazines with high yields. The results showed that the activity of pinacolyl allylboronate was higher than that of allyltrimethylsilane in allylation of trifluoromethylated acylhydrazones.

Key words: trifluoromethylated acylhydrazone, allyltrimethylsilane, pinacolyl allylboronate, allylation, trifluoromethylated homoallylic N-acylhydrazine

Cite this article

Hu Yongqin, Huang Danfeng, Wang Kehu, Zhao Zhuanxia, Zhao Fangxia, Xu Weigang, Hu Yulai. Study on Allylation Reactions of Trifluoromethylated Acylhydrazones with Allylsilanes or Allylboronates[J]. Chinese Journal of Organic Chemistry, 2020, 40(6): 1689-1696.

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三氟甲基酰腙与烯丙基硅或烯丙基硼试剂的烯丙基化反应研究

Study on Allylation Reactions of Trifluoromethylated Acylhydrazones with Allylsilanes or Allylboronates

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