Selectfluor as “Fluorine-Free” Functional Reagent Applied to Organic Synthesis under Transition Metal-Free Conditions

doi:10.6023/cjoc202004005

Abstract

Selectfluor, a commercial electrophilic fluorination reagent with superior performance, is widely used in fluorination reactions. In recent years, Selectfluor has also been widely applied as "fluorine-free" functional reagent in organic synthesis. Especially the application of Selectfluor/transition metals synergetic catalytic system has made great progress. However, this catalytic system has some disadvantages, such as the use of expensive transition metals and environmental unfriendliness. Therefore, more and more attention has been paid to the application of Selectfluor as "fluorine-free" functional reagent under transition metal-free conditions. In this paper, classified by the type of reactions, the research progress of Selectfluor as a "fluorine-free" functional reagent in organic synthesis under transition metal-free conditions is reviewed, and their future outlook is also discussed.

Key words: Selectfluor, “fluorine-free” functional reagent, transition metal-free, organic synthesis

Cite this article

Kong Yaolei, Sun Xiaotong, Weng Jianquan. Selectfluor as “Fluorine-Free” Functional Reagent Applied to Organic Synthesis under Transition Metal-Free Conditions[J]. Chinese Journal of Organic Chemistry, 2020, 40(9): 2641-2657.

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