Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (11): 4384-4390.DOI: 10.6023/cjoc202104016 Previous Articles Next Articles
ARTICLES
收稿日期:
2021-04-08
修回日期:
2021-06-01
发布日期:
2021-08-17
通讯作者:
孟令国
基金资助:
Jinfeng Zhang, Ruyi Ye, Ziyang Li, Lingguo Meng()
Received:
2021-04-08
Revised:
2021-06-01
Published:
2021-08-17
Contact:
Lingguo Meng
Supported by:
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Jinfeng Zhang, Ruyi Ye, Ziyang Li, Lingguo Meng. 1,4-Diazabicyclo[2.2.2]octane-Promoted Addition Reaction of Tricarbonyl Monohydrates with Active Alkynes via Consecutive C—C/C—O Cleavage[J]. Chinese Journal of Organic Chemistry, 2021, 41(11): 4384-4390.
Entry | Solvent | Base | Yieldb |
---|---|---|---|
1 | CH2Cl2 | DABCO | 25c |
2 | CH2Cl2 | DABCO | 36d |
3 | CH2Cl2 | DABCO | 45 |
4 | CH2Cl2 | DABCO | 18e |
5 | CH2Cl2 | DABCO | <10f |
6 | CH2Cl2 | DABCO | Complexg |
7 | CH2Cl2 | Et3N | 13 |
8 | CH2Cl2 | Pyridine | Trace |
9 | CH2Cl2 | DBU | Trace |
10 | CH2Cl2 | DMAP | NDh |
11 | CH2Cl2 | HMTA | NRi |
12 | CH2Cl2 | PPh3 | NDh |
13 | CH2Cl2 | K2CO3 | NRi |
14 | CH2Cl2 | KOBut | NRi |
15 | CHCl3 | DABCO | 17 |
16 | THF | DABCO | 12 |
17 | CCl4 | DABCO | Trace |
18 | CH3CN | DABCO | Trace |
19 | CS2 | DABCO | Trace |
20 | Toluene | DABCO | Trace |
21 | EtOAc | DABCO | Trace |
22 | DMF | DABCO | NDh |
Entry | Solvent | Base | Yieldb |
---|---|---|---|
1 | CH2Cl2 | DABCO | 25c |
2 | CH2Cl2 | DABCO | 36d |
3 | CH2Cl2 | DABCO | 45 |
4 | CH2Cl2 | DABCO | 18e |
5 | CH2Cl2 | DABCO | <10f |
6 | CH2Cl2 | DABCO | Complexg |
7 | CH2Cl2 | Et3N | 13 |
8 | CH2Cl2 | Pyridine | Trace |
9 | CH2Cl2 | DBU | Trace |
10 | CH2Cl2 | DMAP | NDh |
11 | CH2Cl2 | HMTA | NRi |
12 | CH2Cl2 | PPh3 | NDh |
13 | CH2Cl2 | K2CO3 | NRi |
14 | CH2Cl2 | KOBut | NRi |
15 | CHCl3 | DABCO | 17 |
16 | THF | DABCO | 12 |
17 | CCl4 | DABCO | Trace |
18 | CH3CN | DABCO | Trace |
19 | CS2 | DABCO | Trace |
20 | Toluene | DABCO | Trace |
21 | EtOAc | DABCO | Trace |
22 | DMF | DABCO | NDh |
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