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Chinese Journal of Organic Chemistry ›› 2004, Vol. 24 ›› Issue (5): 498-501. Previous Articles     Next Articles

新的核苷衍生物N2,N3-亚乙烯基腺嘌呤核苷的合成

周杰*, 高吉刚   

  1. 山东农业大学化学与材料科学学院 泰安 271018
  • 收稿日期:2003-06-23 修回日期:2003-09-24 接受日期:2003-11-03 发布日期:2022-09-20
  • 基金资助:
    山东省中青年奖励基金(No. 02BS019)资助项目.

Synthesis of a New Nucleoside Derivative N2,N3-Ethenylenoadenosine

ZHOU, Jie*, GAO, Ji-Gang   

  1. College of Chemistry and Material Science, Shandong Agricultural University, Taian 271018
  • Received:2003-06-23 Revised:2003-09-24 Accepted:2003-11-03 Published:2022-09-20
  • Contact: *E-mail: zhoujie@sdau.edu.cn

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The synthesis of new nucleoside derivative N2,N3-ethenylenoadenosine is described. Firstly, guanosine was converted to N2,N3-ethenylenoguanosine through 6 synthetic steps. Then N2,N3-ethenylenoguanosine was converted to title compound by chlorination and ammoniation. The structures of title compound and intermediates were characterized by 1H NMR,MS and HRMS. Preliminary test showed that the title compound had fluorescent character.

Key words: guanosine, N2,N3-ethenylenoadenosine, synthesis