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Chinese Journal of Organic Chemistry ›› 2004, Vol. 24 ›› Issue (11): 1461-1464. Previous Articles     Next Articles

新型卤代羟基三苯醚的合成与抑菌活性研究

辛莹a, 王玉良*,a, 马梦林a, 陈淑华a, 陈洪超a, 杨志荣b, 廖薇b   

  1. a四川大学化学学院 成都 610064;
    b四川大学生命科学学院 成都 610064
  • 收稿日期:2004-01-31 修回日期:3004-04-13 接受日期:2004-06-01 发布日期:2022-09-21
  • 通讯作者: * E-mail: iamxinying@sohu.com
  • 基金资助:
    四川省科技厅(No. 02GY029037)资助项目.

Synthesis and Antimicrobial Activities of Halogenated Hydroxy Triphenyl Ethers

XIN Yinga, WANG Yu-Liang*,a, MA Men-Linga, CHEN Shu-Huaa, CHEN Hong-Chaoa, YANG Zhi-Rongb, LIAO Weib   

  1. aFaculty of Chemistry, Sichuan University, Chengdu 610064;
    bFaculty of Life Science, Sichuan University, Chengdu 610064
  • Received:2004-01-31 Revised:3004-04-13 Accepted:2004-06-01 Published:2022-09-21

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p (m, o)-Benzenediol di(4-chloro-2-hydroxyphenyl) ethers (4a～4c) and p (m, o)-benzenediol di(4-chloro-5-bromo-2-hydroxyphenyl) ethers (5a～5c) were synthesized, and their structures were characterized by 1H NMR, IR, MS spectra and elemental analysis. Their antimicrobial activitieswere investigated, and the preliminary results indicate that they have good antimicrobial activities on Escherichia coli (E. coli), Staphylococcus aureaus(S. aureus), Candida albicans (C. albicans), Staphylococcus albus (S. albus), Proteus vulgaris (P. vulgaris), Diplococcus catarrhalis (D. cata), Pseudomona ssolanacearum (P. solanacearum).

Key words: halogenated hydroxy triphenyl ether, antimicrobial activity, synthesis