化学学报 ›› 1983, Vol. 41 ›› Issue (6): 514-518. 上一篇    下一篇

研究论文

固液相烃基化反应的研究 I.以碳酸钾为碱的丙二酸乙二酯和氰乙酸乙酯的烃基化反应

彭祥运;徐成治   

  1. 安徽中医学院药学系;上海第一医学院药学系
  • 发布日期:1983-06-15

Alkylation in solid-liquid two phase systems i. alkylation of diethyl malonate and ethyl cyanoacetate using potassium carbonate as a base

PENG XIANGYUN;XU CHENGZHI   

  • Published:1983-06-15

关键词: 反应机理, 乙酯, 烷基化, 碳酸钾, 羧酸酯, 丙二酸 P, 氰乙酸 P

The alkylation of diethyl malonate and ethyl cyanoacetate using powdered potassium carbonate asa base in the absence of solvent and other catalyst is studied. The features of this method are: simple preparative procedure, reproducible yield and easy control of monoalkylation. The reaction mechanism is discussed briefly.

Key words: REACTION MECHANISM, ETHYL ESTER, ALKYLATION, POTASSIUM CARBONATE, CARBOXYLIC ACID ESTER, MALONIC ACID P, CYANOACETIC ACID P

中图分类号: