有机化学 ›› 2021, Vol. 41 ›› Issue (3): 1072-1080.DOI: 10.6023/cjoc202007049 上一篇    下一篇

综述与进展

卤素盐参与下有机电合成含氮杂环化合物的研究进展

周娅琴a, 赵志恒a, 曾亮a, 李鸣a, 何永辉a,*(), 谷利军a,b,*()   

  1. a 云南民族大学民族医药学院 民族药资源化学教育部重点实验室 昆明 550025
    b 贵州大学精细化工研究开发中心 绿色农药和农业生物工程教育部重点实验室 贵阳 550025
  • 收稿日期:2020-07-21 修回日期:2020-08-29 发布日期:2020-09-22
  • 通讯作者: 何永辉, 谷利军
  • 基金资助:
    国家自然科学基金(21662045); 贵州大学绿色农药实验室开放基金(2018GDGP0103)

Recent Advance in Organic Electrochemical Synthesis of Nitrogenous Heterocyclic Compounds Involving Haloids as Mediators

Yaqin Zhoua, Zhiheng Zhaoa, Liang Zenga, Ming Lia, Yonghui Hea,*(), Lijun Gua,b,*()   

  1. a Key Laboratory of Chemistry in Ethnic Medicinal Resources, Ministry of Education,School of Ethnic Medicine, Yunnan Minzu University, Kunmin 650500
    b Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025
  • Received:2020-07-21 Revised:2020-08-29 Published:2020-09-22
  • Contact: Yonghui He, Lijun Gu
  • About author:
    * Corresponding authors. E-mail: ,

含氮杂环化合物广泛存在于医药、农药及天然产物中, 是许多具有生理活性的化合物和药物的基本骨架. 开发高效、绿色的含氮杂环化合物的构建方法具有重要意义. 近年来, 卤素盐参与下有机电合成含氮杂环化合物取得了诸多进展. 该类反应具有操作简单、绿色环保等特点. 综述了有机电化学合成反应中, 卤素盐作媒介, 含氮杂环化合物的合成研究新进展.

关键词: 卤素盐, 电化学合成, 含氮杂环

Nitrogenous heterocyclic compounds are widely found in medicinal molecules, natural products and functional materials. Therefore, it has great significance to develop simple and efficient methods for the construction of these compounds. Recently, remarkable progress has been made in haloids mediated electrochemical synthesis of nitrogen heterocycles. Due to the relatively mild reaction condition and environmental protection, it provides a novel approach to construct nitrogen heterocycles. In this review, the recent developments in this area are summarized.

Key words: haloids, electrochemical synthesis, nitrogenous heterocyclic compounds