有机化学 ›› 2022, Vol. 42 ›› Issue (9): 2745-2759.DOI: 10.6023/cjoc202204002 上一篇    下一篇

综述与进展

亚砜叶立德参与构建五/六元氮杂环的反应研究进展

张建涛*(), 张聪, 郑梓栋, 周鹏, 刘卫兵   

  1. 广东石油化工学院化学学院 广东茂名 525000
  • 收稿日期:2022-04-01 修回日期:2022-05-28 发布日期:2022-06-08
  • 通讯作者: 张建涛
  • 基金资助:
    广东石油化工学院人才引进计划(2019rc048); 国家自然科学基金(21602035)

Research Progress of Sulfoxonium Ylides in the Construction of Five/Six-Membered Nitrogen-Containing Heterocycles

Jiantao Zhang(), Cong Zhang, Zidong Zheng, Peng Zhou, Weibing Liu   

  1. College of Chemistry, Guangdong University of Petrochemical Technology, Maoming, Guangdong 525000
  • Received:2022-04-01 Revised:2022-05-28 Published:2022-06-08
  • Contact: Jiantao Zhang
  • Supported by:
    Projects of Talents Recruitment of Guangdong University of Petrochemical Technology(2019rc048); National Natural Science Foundation of China(21602035)

亚砜叶立德因其在有机合成中的高稳定性和多样的反应性, 被视为各种有机转化的强大试剂. 系统综述了亚砜叶立德参与构建含氮杂环化合物的反应研究进展, 总结了亚砜叶立德作为重要合成子在构建吡咯、咪唑、吲哚、喹啉、喹喔啉、噌啉等五元、六元含氮杂环化合物的新方法和新进展, 并展望了亚砜叶立德绿色合成氮杂环的未来发展趋势.

关键词: 亚砜叶立德, 有机转化, 含氮杂环, 绿色合成

Sulfoxonium ylides are witnessed as powerful reagents for various organic transformations due to its high stability and diverse reactivity in organic synthesis. The research progress of sulfoxonium ylides involved in the construction of nitrogen-containing heterocyclic compounds is systematically summarized. The new methods and progress of sulfoxonium ylides as an important synthon to construct five-membered and six-membered nitrogen-containing heterocyclic compounds, such as pyrrole, imidazole, indole, quinoline, quinoxaline, and cinnoline, are summarized, and the future development trend of green synthesis of nitrogen heterocycles from sulfoxonium ylides is also prospected.

Key words: sulfoxonium ylides, organic transformation, nitrogen-containing heterocycles, green synthesis