有机化学 ›› 1997, Vol. 17 ›› Issue (4): 349-353. 上一篇    下一篇

研究论文

1-芳酰基-4-菊酰基氨基硫脲类化合物的合成及生物活性

金桂玉;侯震;任军;赵国锋   

  1. 南开大学元素有机化学研究所
  • 发布日期:1997-08-25

The synthesis and biological activity of 1-aroyl-4-chrysanthemoyl thiosemicarbazides

JIN GUIYU;HOU ZHEN;REN JUN;ZHAO GUOFENG   

  • Published:1997-08-25

本文利用菊酰基异硫氰酸酯与芳基酰肼的加成反应合成了16个新的酰氨基硫脲类化合物,其结构经^1H NMR,IR,MS和元素分析所确证,生物活性测定表明它们具有一定杀菌活性。

关键词: 结构表征, 酰胺基, 异硫氰酸酯 P, 生物活性, 酰肼 P, 加成反应, 杀菌剂, 硫脲类, 有机合成

Sixteen of 1-aroyl-4-chrysanthemoyl thiosemicarbazides were synthesized by addition reaction of chrysanthemoyl isothiocyanates with aroyl hydrazines, whose structures were characterized by ^1H NMR, IR, MS and elementary analysis. The biological tests indicated that these compounds had fungicidal activity.

Key words: STRUCTURE CHARACTERISTICS, AMIDO, BACTERICIDAL AGENTS, ADDITION REACTION, HYDRAZIDE P, SULFOCARBAMIDES, ORGANIC SYNTHESIS, BIOLOGICAL ACTIVITY

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