有机化学 ›› 2014, Vol. 34 ›› Issue (5): 948-955.DOI: 10.6023/cjoc201311042 上一篇    下一篇

研究论文

锡粉促进下由醛、芳甲酰肼和烯丙基溴“一锅法”合成高烯丙基酰肼化合物

陆爱玲, 王凤娇, 黄丹凤, 王克虎, 苏瀛鹏, 徐艳丽, 胡雨来   

  1. 西北师范大学化学化工学院 兰州 730070
  • 收稿日期:2013-11-26 修回日期:2014-01-09 发布日期:2014-01-22
  • 通讯作者: 胡雨来,黄丹凤 E-mail:huyl@nwnu.edu.cn;huangdf@nwnu.edu.cn
  • 基金资助:

    国家自然科学基金(No. 21062016)资助项目.

Tin-Mediated “One-Pot” Synthesis of Homoallylhydrazides from Aldehydes, Aryl Acylhydrazines and Allyl Bromide

Lu Ailing, Wang Fengjiao, Huang Danfeng, Wang Kehu, Su Yingpeng, X? Yanli, Hu Yulai   

  1. College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070
  • Received:2013-11-26 Revised:2014-01-09 Published:2014-01-22
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21062016).

报道了锡粉促进下,以四氢呋喃(THF)为溶剂,在室温条件下,通过醛、芳甲酰肼和烯丙基溴“一锅法”反应,合成高烯丙基酰肼化合物的方法.该方法具有条件温和,不使用任何催化剂,操作简单,产率高等优点.

关键词: 一锅法, 锡粉, 醛, 酰肼, 高烯丙基酰肼

An one-pot reaction was developed for the synthesis of homoallylhydrazides by treating aldehydes, aryl acylhydrazines and allyl bromide with tin powder at room temperature in tetrahydrofuran. The reaction proceeded smoothly without using any catalyst under mild conditions to give the corresponding products in high yields.

Key words: one pot, tin powder, aldehydes, acylhydrazines, homoallylhydrazides