有机化学 ›› 2015, Vol. 35 ›› Issue (3): 705-711.DOI: 10.6023/cjoc201408028 上一篇    下一篇

研究论文

一种卡宾配合物的合成及其在Suzuki反应中的应用

唐演a, 杨飞飞a, 聂士鹏a, 王林a, 罗治斌b, 陆鸿飞a   

  1. a 江苏科技大学环境与化学工程学院 镇江 212003;
    b 江苏大学化工学院 镇江 212003
  • 收稿日期:2014-08-25 修回日期:2014-11-04 出版日期:2015-03-25 发布日期:2014-11-13
  • 通讯作者: 陆鸿飞 E-mail:zjluhf1979@hotmail.com
  • 基金资助:

    国家自然科学基金(No. 21402067)资助项目.

Synthesis of a Carbene Complex and Its Application in Suzuki Reaction

Tang Yana, Yang Feifeia, Nie Shipenga, Wang Lin Luo Zhibina, Lu Hongfeib   

  1. a School of Envionmental and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang 212003;
    b School of Chemical Engineering, Jiangsu University, Zhenjiang 212003
  • Received:2014-08-25 Revised:2014-11-04 Online:2015-03-25 Published:2014-11-13
  • Supported by:

    Project supported by the National Natual Science Foundation of China (No. 21402067).

合成了一种N-杂环卡宾的钯配合物, 可用于高效地催化芳基溴化物和对甲苯磺酸芳酯对芳基硼酸的Suzuki偶联反应. 该反应在二氧六环溶剂中以醋酸钾为助剂、空气氛下80 ℃即可进行, 具有收率高、催化剂容易制备等优点.

关键词: Suzuki偶联反应, 卡宾, 钯配合物, 合成

A palladium N-heterocyclic (NHC) complex has been synthesized and successfully developed as an efficient catalyst for the Suzuki coupling reaction of aryl bromides and 4-toluene sulfonic acid aromatic esters with aryl boronic acids. The catalytic reaction proceeded smoothly in dioxane with potassium acetate as the additive at 80 ℃ in an air atmosphere, while the yield of the target product is excellent and the catalyst can be synthesized easily.

Key words: Suzuki coupling reaction, carbene, palladium complex, synthesis