1,3-苯并噻嗪酮类衍生物合成方法的研究进展

doi:10.6023/cjoc201603034

有机化学 ›› 2016, Vol. 36 ›› Issue (9): 2024-2038.DOI: 10.6023/cjoc201603034 上一篇下一篇

综述与进展

1,3-苯并噻嗪酮类衍生物合成方法的研究进展

李闪闪, 洪海龙, 竺宁, 韩利民, 吕佳媛

内蒙古工业大学化工学院呼和浩特 010051

收稿日期:2016-03-20 修回日期:2016-05-06 发布日期:2016-05-19
通讯作者: 洪海龙, 竺宁 E-mail:honghailong_1979@163.com;zhuning2622@yahoo.com
基金资助:
国家自然科学基金（Nos.21362019，21666026）、内蒙古自然科学基金（No.2016MS0207）、内蒙古自治区教育厅研究生科研创新基金（No.S20151012805）资助项目.

Review About the Synthesis of 1,3-Benzothiazinone Derivatives

Li Shanshan, Hong Hailong, Zhu Ning, Han Limin, Lü Jiayuan

Chemical Engineering College, Inner Mongolia University of Technology, Hohhot 010051

Received:2016-03-20 Revised:2016-05-06 Published:2016-05-19
Supported by:
Project supported by the National Natural Science Foundation of China (Nos.21362019, 21666026), the Natural Science Foundation of Inner Mongolia (No.2016MS0207) and the Graduate Student Scientific Research Innovation Foundation of the Department of Education of Inner Mongolia Autonomous Region (No.S20151012805).

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摘要/Abstract

1,3-苯并噻嗪酮类衍生物具有广泛的生物学活性，因此这类衍生物的合成方法备受关注.从引入硫原子的方式及反应机理的角度，归纳总结了以苯硫酚类衍生物、二硫化物、同碳上连有胺基和巯基类衍生物、异硫氰酸酯类衍生物与小分子硫源等为原料合成1,3-苯并噻嗪酮类衍生物的方法.

关键词: 1,3-苯并噻嗪酮, 硫源, 合成方法, 反应机理

1,3-Benzothiazinone derivatives have widely bioactivities. So the methods for the synthesis of these 1,3-benzothiazinone derivatives have attracted enormous attentions worldwide. From the method of introducing sulfur atom and the reaction mechanism for the formation of benzothiazinone derivatives, the method of synthesizing 1,3-benzothiazinone derivatives has been summarized in this review. So the thiophenol derivatives, disulfide derivatives, the same carbon connected with amino and mercapto derivatives, isothiocyanate derivatives and some smaller sulfur molecules are used as starting materials.

Key words: 1,3-benzothiazinone, sulfur source, synthetic methods, reaction mechanism

引用此文

李闪闪, 洪海龙, 竺宁, 韩利民, 吕佳媛. 1,3-苯并噻嗪酮类衍生物合成方法的研究进展[J]. 有机化学, 2016, 36(9): 2024-2038.

Li Shanshan, Hong Hailong, Zhu Ning, Han Limin, Lü Jiayuan. Review About the Synthesis of 1,3-Benzothiazinone Derivatives[J]. Chin. J. Org. Chem., 2016, 36(9): 2024-2038.

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1,3-苯并噻嗪酮类衍生物合成方法的研究进展

Review About the Synthesis of 1,3-Benzothiazinone Derivatives

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