Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (02): 203-223.DOI: 10.6023/cjoc201209022 Previous Articles     Next Articles



李丹丹, 何程林, 蔡海婷, 王官武   

  1. 中国科学技术大学化学系 合肥 230026
  • 收稿日期:2012-09-17 修回日期:2012-10-19 发布日期:2012-10-26
  • 通讯作者: 王官武
  • 基金资助:

    国家自然科学基金(No. 21132007)和安徽省高校省级自然科学研究重大(No. KJ2010ZD05)资助项目.

Palladium-Catalyzed Group-Directed sp2-C—H Functionalization

Li Dandan, He Chenglin, Cai Haiting, Wang Guanwu   

  1. Department of Chemistry, University of Science and Technology of China, Hefei 230026
  • Received:2012-09-17 Revised:2012-10-19 Published:2012-10-26
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21132007) and the Key Project of Science and Technology of the Department of Education, Anhui Province (No. KJ2010ZD05).

Recently, palladium-catalyzed direct C—H bond functionalization has emerged as the most useful and important methods to construct C—C bond, C—N bond, C—O bond and C—X (Cl, Br, I) bond in organic synthesis. Directing group-assisted selective activation of C—H bond has been received increasing attention. This review mainly covers the recent advances in the versatility and practicality of directing group-assisted sp2-C—H functionalization.

Key words: palladium-catalyzed, ligand-directed, sp2-C—H bonds activation, functionalization, cross-coupling reaction