Chin. J. Org. Chem. ›› 2014, Vol. 34 ›› Issue (8): 1588-1594.DOI: 10.6023/cjoc201402040 Previous Articles     Next Articles



孟团结, 刘澜涛, 任利锋, 刘新明, 王晓娟, 赵文献   

  1. 商丘师范学院化学化工学院 有机新材料合成重点实验室 商丘 476000
  • 收稿日期:2014-02-28 修回日期:2014-04-28 发布日期:2014-05-05
  • 通讯作者: 刘澜涛,赵文献,
  • 基金资助:


One-Pot Three-Component Synthesis of Novel Carbamate Compounds Mediated by Zinc Powder

Meng Tuanjie, Liu Lantao, Ren Lifeng, Liu Xinming, Wang Xiaojuan, Zhao Wenxian   

  1. Key Laboratory of New Organic Materials Synthesis, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000
  • Received:2014-02-28 Revised:2014-04-28 Published:2014-05-05
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. U1204204) and the Youth Foundation of Shangqiu Normal University (No. 2011QN17).

A series of novel carbamate compounds were obtained from one pot three component reaction of aldehydes, bromohydrocarbons and isocyanates mediated by zinc powder under room temperature. This protocol has advantages of mild conditions, simple work-up, high yield, easily available starting materials and fast reaction rate. The structures of all products were characterized by 1H NMR, 13C NMR, IR, HRMS and elemental analysis.

Key words: carbamate compounds, zinc powder, one-pot, three-component, synthesis