Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (11): 2559-2582.DOI: 10.6023/cjoc201606012 Previous Articles     Next Articles



张惠敏, 吴彦城, 尤嘉宜, 曹梁, 丁沙, 蒋凯, 汪朝阳   

  1. 华南师范大学化学与环境学院 教育部环境理论化学重点实验室 广州 510006
  • 收稿日期:2016-06-06 修回日期:2016-06-28 发布日期:2016-07-15
  • 通讯作者: 吴彦城, 汪朝阳;
  • 基金资助:


New Progress in the Design, Synthesis and Application of Fluorescent Probes for Fluoride Ion Detection

Zhang Huimin, Wu Yancheng, You Jiayi, Cao Liang, Ding Sha, Jiang Kai, Wang Zhaoyang   

  1. Key Laboratory of Theoretical Chemistry of Environment, Ministry of Education, School of Chemistry and Environment, South China Normal University, Guangzhou 510006
  • Received:2016-06-06 Revised:2016-06-28 Published:2016-07-15
  • Supported by:

    Project supported by the Natural Science Foundation of Guangdong Province (No.2014A030313429) and the 3rd Talents Special Funds of Guangdong Higher Education (No.Guangdong-Finance-Education[2011]431),Guangzhou Science and Technology Project Scientific Special (No.201607010251).

The recognition and detection of trace fluoride ions in vivo and vitro have attracted great attention in recent years. More and more new fluorescent probes (FP) for fluoride ion detection have been designed and synthesized due to their advantages, such as high sensitivity, good selectivity and convenient operation. According to the different structural features and recognition mechanism, fluoride ion FP can be classified into two categories as deprotonation and reaction type. The new progress especially in recent three years on their molecular design, synthesis and application is reviewed on the viewpoint of green chemistry. The future trend of fluoride ion FP is also prospected.

Key words: fluoride ion, fluorescent probe, molecular design, synthesis, green chemistry