Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (6): 1382-1391.DOI: 10.6023/cjoc201612031 Previous Articles     Next Articles



廖进喜, 刘慧, 孙建松   

  1. 江西师范大学国家单糖化学合成工程技术研究中心 南昌 330022
  • 收稿日期:2016-12-08 修回日期:2017-02-13 发布日期:2017-02-27
  • 通讯作者: 孙建松
  • 基金资助:


Applications of Transition Metal Catalyzed Coupling Reactions in the Synthesis of C-Glycosides

Liao Jinxi, Liu Hui, Sun Jiansong   

  1. National Engineering Research Center for Carbohydrate Synthesis, Jianxi Normal University, Nanchang, 330022
  • Received:2016-12-08 Revised:2017-02-13 Published:2017-02-27
  • Contact: 10.6023/cjoc201612031
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21202166) and the Science and Technology Project Founded by the Education Department of Jiangxi Province (No. GJJ150328).

C-Glycosides in which the interglycosidic oxygen atom have been replaced by carbon atom are widely found in natural products and drug molecules. They have better enzymatic and hydrolytic stablility compared to their corresponding O-glycosides and N-glycosides. The syntheses of them have received considerable attention because of their unique chemical structure and extensive application value. Rencent advances in the synthesis of C-glycosides through coupling reactions catalyzed by transition metal are summarized in this review. A summary of the advantages and disadavatages of different synthetic methods will be beneficial to the develepment of new synthetic method for C-glycosides.

Key words: C-glycosides, synthesis, transition metal catalyzed, coupling reactions