Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (3): 661-667.DOI: 10.6023/cjoc201808015 Previous Articles     Next Articles

Reviews

铜催化下含氮化合物的Chan-Lam偶联反应的研究进展

段希焱, 刘宁, 王佳, 马军营   

  1. 河南科技大学化工与制药学院 洛阳 471023
  • 收稿日期:2018-08-16 修回日期:2018-09-22 出版日期:2019-03-25 发布日期:2018-10-26
  • 通讯作者: 段希焱 E-mail:duanxiyan@tju.edu.cn
  • 基金资助:

    河南省科技攻关(No.182102310106)资助项目.

Progress in Copper-Catalyzed Chan-Lam Coupling of N-Compounds

Duan Xiyan, Liu Ning, Wang Jia, Ma Junying   

  1. School of Chemical Engineering & Pharmaceutics, Henan University of Science and Technology, Luoyang 471023
  • Received:2018-08-16 Revised:2018-09-22 Online:2019-03-25 Published:2018-10-26
  • Contact: 10.6023/cjoc201808015 E-mail:duanxiyan@tju.edu.cn
  • Supported by:

    Project supported by the Science and Technology Foundation of Henan Province (No. 182102310106).

Construction of C-N bond is one of the most important areas in synthetic organic chemistry and medical chemistry. Many synthetic methods for the construction of C-N bond have been reported over the past few years. Copper-catalyzed Chan-Lam reactions represent one of the most powerful and straightforward tools to construct C-N bonds. In this paper, the recent progress in Chan-Lam coupling of N-compounds with (hetero) aryl boronates to construct C-N bond based on the reaction mechanism, reaction system, the scope of substrates, etc., is reviewed.

Key words: Chan-Lam coupling, copper-catalyzed, C-N bond, aryl boronates, N-compounds