Chinese Journal of Organic Chemistry ›› 2019, Vol. 39 ›› Issue (10): 2980-2984.DOI: 10.6023/cjoc201904001 Previous Articles     Next Articles

Special Issue: 荧光探针-生物传感合辑 有机超分子化学合辑



刘钰a, 汤永星c, 罗月阳c, 朱叶婷c, 杨进c, 魏欣雨c, 刘雄c, 赵云辉abc*()   

  1. a 河南工业大学小麦和玉米深加工国家工程实验室 郑州 450001
    b 中国科学院上海有机化学研究所 天然产物有机合成化学重点实验室 上海 200032
    c 湖南科技大学化学化工学院 精细聚合物可控制备及功能应用湖南省重点实验室 湘潭 411201
  • 收稿日期:2019-04-01 修回日期:2019-05-05 发布日期:2019-05-21
  • 通讯作者: 赵云辉
  • 基金资助:
    河南工业大学小麦和玉米深加工国家工程实验室开放课题(No. NL2018006)

Synthesis and Application of Fluorescent Probe Containing Barbitone Unit

Liu, Yua, Tang, Yongxingc, Luo, Yueyangc, Zhu, Yetingc, Yang, Jinc, Wei, Xinyuc, Liu, Xiongc, Zhao, Yunhuiabc*()   

  1. a National Engineering Laboratory for Wheat & Corn Further Processing, Henan University of Technology, Zhengzhou 450001;
    b Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
    c Hunan Provincial Key Laboratory of Controllable Preparation and Functional Application of Fine Polymers, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201
  • Received:2019-04-01 Revised:2019-05-05 Published:2019-05-21
  • Contact: Zhao, Yunhui
  • Supported by:
    Project supported by the Open Project of the National Engineering Laboratory for Wheat & Corn Further Processing, Henan University of Technology(No. NL2018006)

Mercury ion pollution has serious harmful impact on the ecological environment and human health. It is of great significance to develop a probe with high selectivity and sensitivity that could be applied to the detection of mercury ion in water environment. In this paper, a novel excited-state intramolecular proton transfer (ESIPT) fluorescent probe containing barbitone unit was designed and synthesized from salicylaldehyde. Mechanism studies showed that mercury ions and probes formed a structure similar to “(thymine)T-Hg-T” which has high selectivity in determining mercury ions. The calibration curve indicated that there was a good linear correlation between the relative fluorescent intensities over the concentration range of 4~20 μmol·L –1 of Hg 2+ ion.

Key words: fluorescent probe, mercury ion, barbitone, excited-state intramolecular proton transfer (ESIPT)