Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (1): 140-148.DOI: 10.6023/cjoc201905054 Previous Articles     Next Articles

Special Issue: 有机光催化合辑

光诱导的二芳基烯丙醇氰甲基化合成δ-酮腈的反应研究

杜琳琳, 李铁生   

  1. 郑州大学化学与分子工程学院 河南省化学生物与有机化学重点实验室 河南省高等学校应用化学重点开放实验室 郑州 450052
  • 收稿日期:2019-05-31 修回日期:2019-08-24 发布日期:2020-02-06
  • 通讯作者: 李铁生 E-mail:lts34@zzu.edu.cn

Visible-Light Induced Cyanomethylation of Diaryl Allyl Alcohols to Synthesize δ-Ketonitriles

Du Linlin, Li Tiesheng   

  1. Henan Key Laboratory of Chemical Biology and Organic Chemistry, Key Laboratory of Applied Chemistry of Henan Universities, College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450052
  • Received:2019-05-31 Revised:2019-08-24 Published:2020-02-06

A photocatalyzed method for the synthesis of δ-ketonitriles from the reaction of diaryl allyl alcohols with bromoacetonitrile is developed. The result of control experiments indicates that the reaction might proceed via a free radical mechanism and bromoacetonitrile was the source of cyanomethyl radical.

Key words: photocatalyzed, diaryl allyl alcohol, radical