Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (3): 589-597.DOI: 10.6023/cjoc201909032 Previous Articles     Next Articles

无过渡金属体系下C (sp2)—H键的自由基反应构建C—N键研究进展

吴燕a,c, 陈锦杨a,c, 李强b, 魏文廷c   

  1. a 长江师范学院化学化工学院 重庆 408000;
    b 聊城大学化学化工学院 山东聊城 252059;
    c 宁波大学材料科学与化学工程学院 浙江宁波 315211
  • 收稿日期:2019-09-22 修回日期:2019-10-26 发布日期:2020-04-02
  • 通讯作者: 陈锦杨, 魏文廷;
  • 基金资助:

Progress in C—N Bond Formation Involving C(sp2)—H Bond through Transition-Metal-Free Radical Reactions

Wu Yana,c, Chen Jinyanga,c, Li Qiangb, Wei Wentingc   

  1. a College of Chemistry and Chemical Engineering, Yangtze Normal University, Chongqing 408000;
    b School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059;
    c School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang 315211
  • Received:2019-09-22 Revised:2019-10-26 Published:2020-04-02
  • Supported by:
    Project supported by the Basic and Frontier Research Project of Chongqing (Nos. Cstc2018jcyjAX0721, Cstc2018jcyjAX0051), the Youth Talent Growth Plan Project of Yangtze Normal University (No. 2018QNRC11) and the Education Commission of Chongqing City (No. KJQN201801404).

The C-N bond is widely found in medicinal molecules, natural products and functional materials. Therefore, it has great significance to develop simple and efficient methods for the construction of C-N bond. Recently, remarkable progress has been made in construction of C-N bond involving C(sp2)-H bond through transition-metal-free radical reactions. Due to the relatively mild reaction condition and high reactivity, it provides a novel approach to construct C-N bond. In this review, the recent developments in this area are summarized on the basis of different nitrogen sources.

Key words: C—N bond, C (sp2)—H bond, transition-metal-free, radical