Chin. J. Org. Chem. ›› 1998, Vol. 18 ›› Issue (5): 481-485. Previous Articles     Next Articles

Original Articles

硫脲类衍生物及其生物活性研究

黄志纾;吴晓琳;刘煜;蒋腊生;王植材;古练权   

  1. 中山大学化学系.广州(510275)
  • 发布日期:1998-10-25

The synthesis and biological activity of alkyl 4-aryl-3-thio- allophanate

Huang Zhishu;Wu Xiaolin;Liu Yu;Jiang Lasheng;Wang Zhicai;Gu Lianquan   

  1. Zhongshan Univ., Dept Chem.Guangzhou(510275)
  • Published:1998-10-25

Ten thiourea derivatives, the alkyl 4-aryl-3-thio-allophanates (1~ 10) have been synthesized by the reactions of different arylamine with alkoxycarbonyl isothiocyanates which was prepared from Me or Et chloroformate and potassium thiocyanate. The biological activity of 1 ~10, has also been investigated.

Key words: ALKOXY COMPLEX, SYNTHESIS, ISOTHIOCYANATE, FORMIC ESTER, AROMATIC AMINES, CARBONOCHLORIDIC ACID P, POTASSIUM THIOCYNATE, BIOLOGICAL ACTIVITY, STRUCTURE CHARACTERISTICS, SULFOCARBAMIDES

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