Chin. J. Org. Chem. ›› 1999, Vol. 19 ›› Issue (4): 364-372. Previous Articles     Next Articles

Original Articles

D-奎尼酸: 一个多用途的手性合成子

黄培强   

  1. 厦门大学化学系.厦门(361005)
  • 发布日期:1999-08-25

D-quinic acid, a versatile chiron in organic synthesis

Huang Peiqiang   

  1. Xiamen Univ, Dept Chem.Xiamen(361005)
  • Published:1999-08-25

This review describes the use of D-Quinic acid in the synthesis of various natural or un-natural bioactive compounds. Because of the presence of cis-γ -hydroxyl-carboxyl subunit in quinic acid, a lactone ring can be formed easily. The thus formed rigid system provides good control elements for many regio- and stereoselective transformations. Besides, D-quinic acid is also readily available. These make this compound a useful and versatile chiron for both cyclic (hexanoids and pentanoids) and acyclic bioactive compounds.

Key words: SYNTHESIS

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